Dr AJ Halahakoon
Email: halakoonhmaj@kdu.ac.lk
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Academia
Qualification
Teaching Areas
Research Interest
Other
Publications
Qualification
- PhD in Pharmaceutical Sciences (Peoples’ Friendship University of Russia)
- MSc in Pharmaceutical Sciences (Voronezh state University Russia)
- Certified specialist in Pharmacy (Russia)
- Certificate Course in Teaching in Higher Education at KDU
Teaching Areas
- Pharmaceutical Technology
- Physical Pharmacy
- Pharmaceutical Chemistry
- Pharmaceutical Biotechnology
- Drug delivery systems and nanotechnology
- Computer aid Drug design.
Research Interest
- Drug delivery systems (DDS), targeted drug delivery, Cell-based drug delivery, a nanotechnological approach for the development of novel drug delivery systems for anticancer drugs.
- Screening novel active pharmaceutical compounds from natural resources.
- Nanotechnological approaches for targeted drug delivery and designing novel DDS based on nanotechnology.
- Developments of new analytical methods/techniques for quality assessment and standardizations of novel drug forms and substances.
- Small heterocyclic molecules with anticancer, antimicrobial, antiviral, antiinflammation, anti-tuberculosis properties.
- Solid and liquid dosage formulations development.
- Molecular modeling, drug designed and bioinformatics.
Other
- Member of the Subject Expert Panel of Pharmacist at Ceylon Medical Collage council since 01st August 2022.
Other responsibilities
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Publications
Books
- Encapsulation of indole alkaloids into erythrocyte carriers (originally in Russian language) (Инкапсулирование терпено индольных алкалоидов в эритроцитарные носители), LAP Lambert Academic Publishing – ISBN-13: 978-620-0-00865-7 ISBN-10: 6200008655 EAN: 9786200008657 –
- Halahakoon Mudiyanselage Amila Jeewantha Halahakoon (Democratic Socialist Republic of Sri Lanka) THE OBTAINED AND STANDARDIZATION OF ENCAPSULATED ERYTHROCYTES CARRIER WITH TERPENE-INDOLES ALKALOIDS ANTICANCER DRUGS 14.04.02. – Pharmaceutical chemistry, pharmacognosy, Abstracts of Dissertations for the scientific degree of candidate of pharmaceutical sciences Moscow – 2018 https://search.rsl.ru/en/record/01008699746?ysclid=lyztai7at1856316881
- [ Original document in Russian – Халахакун Мудиянселаге Амила Дживанта Халахакун.
- Получение и стандартизация эритроцитарных носителей, инкапсулированных терпено-индольными алкалоидными противоопухолевыми препаратами: автореферат дис. … кандидата фармацевтических наук: 14.04.02 / Халахакун Мудиянселаге Амила Дживанта Халахакун; [Место защиты: Рос. ун-т дружбы народов]. – Москва, 2018. – 26 с.
- Фармацевтическая химия и фармакогнозия
- Здравоохранение. Медицинские науки — Фармакология — Противоопухолевые средства — Исследование и контроль Шифр хранения:OD 9 19-14/61]
Referred Journal articles
- Halahakoon Amila Jeewantha, Slivkin Aleksei Ivanovich, Karlov Pavel Mihailovich. Validated spectrophotometric method for the estimation of vincristine and vinblastine. Int J Pharm Pharm Sci 2017;9(4)
- Jeewantha HMA, Slivkin AI. The terpene-indole alkaloids loaded erythrocytes as a drug carrier: design and assessment. Russian Open Medical Journal 2018; 7: e0406.
- Jeewantha Halahakoon Mudiyanselage Amila. “Systems for the delivery of chemotherapeutic drugs, new approaches and perspective” Russian Open Medical Journal, vol. 6, no. 3, 2017, pp. 302.
- Trineeva O.V., Halahakoon A.J., Slivkin A.I., Chupandina E.E. morphological and physico-chemical properties of erythrocyte carriers encapsulated by terpineindolic alkaloids. Drug development & registration. 2018;(1):146-150. (In Russ.)
- Trineeva O.V., Halahakoon A.J., Slivkin A.I. CELL CARRIERS AS SYSTEMS OF DELIVERY OF ANTITUMOR DRUGS (REVIEW). Drug development & registration. 2019;8(1):43-57. (In Russ.) https://doi.org/10.33380/2305-2066-2019-8-1-43-57
- Trineeva O.V., Halahakoon A.J. Study of Desorption and Exemption of Terpeno-indole Alkaloids of Vincristine and Vinblastine from Erythrocyte Cell Carriers. Drug development & registration. 2019;8(2):16-21. (In Russ.) https://doi.org/10.33380/2305-2066-2019-8-2-16-21
- Trineeva O.V., Halahakoon A.J., Slivkin A.I. cell carriers as systems of delivery of antitumor drugs (review). Drug development & registration. 2019;8(1):43-57. (In Russ.) https://doi.org/10.33380/2305-2066-2019-8-1-43-57
- Trineeva O.V., Halahakoon A.J., and Slivkin A.I. “Development and validation of methods for spectrophotometric quantitative determination of terpene-indole alkaloids (using the example of vincristine sulfate and vinblastine sulfate)” Current problems of medicine, vol. 41, no. 4, 2018, pp. 687-702. [ Тринеева О.В., Халахакун А.Д., and Сливкин А.И. “Разработка и валидация методик спектрофотометрического количественного определения терпено-индольных алкалоидов (на примере винкристина сульфата и винбластина сульфата)” Актуальные проблемы медицины, vol. 41, no. 4, 2018, pp. 687-702.]
- Slivkina I, Kondrashina OV, Halahakoon MAJ, Belenova AS. DNA based hybrid liquid crystalline nano organometallic composites for targeted drug delivery in neutron capture therapy. Int J Pharm Pharm Sci 2017;9(6):74-79.
- Aleksandrovna, P. Y., S. A. Ivanovich, and H. A. Jeewantha. “Validation of assay procedures of afobazole in microcapsules”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 9, no. 5, May 2017, pp. 278-81, doi:10.22159/ijpps.2017v9i5.16684.
- : Polkovnikova Y, Koryanova K, Jeewantha HA. Quantum-chemical free energy calculation of vinpocetine molecule release from sodium alginate. Marmara Pharm J. 2018; 22 (3): 443-449. https://doi.org/10.12991/jrp.2018.85
- O. V. Trineeva, A. I. Slivkin, A. J. Halahakoon methods of qualitative and quantitative determination of terpen-indoal alkaloids of the plant of the genus catharanthus (review), BULLETIN OF VSU, SERIES: CHEMISTRY. BIOLOGY. PHARMACY, 2019, no.4, 109-120. http://www.vestnik.vsu.ru/pdf/chembio/2019/04/2019-04-16.pdf
Conference papers
- HMAJ Halahakoon The assessment of the capping tendency of the tablet during the pharmaceutical tabletting using finite element analysis in computational modelling tools – General Sir John Kotelawala Defence University – 15th International Research Conference 2022.
- Halahakoon Amila Jeewantha, NRM Nelumdeniya MJJH Fernando, SC Ilangamge In-Vitro Evaluation of Gastroprotective Activity and Phytochemical Screening of the Aqueous Leaf Extract of Cyclea peltate General Sir John Kotelawala Defence University – 15th International Research Conference 2022.
- HMAJ Halahakoon, In silico study of the computationally designed novel Vinca alkaloid derivatives VADRPA01 and VADRPH01 effects on Calmodulin and Calmodulin dependent Ca2+ transport ATPase, General Sir John Kotelawala Defence University – 16th International Research Conference 2023.
- AJ Halahakoon, OV Trineeva Study of the stability and shelf life of cellular forms of terpene-indole alkaloids vincristine and vinblastine, Publication date 2018 Conference materials – WAYS AND FORMS OF IMPROVING PHARMACEUTICAL EDUCATION. CURRENT ISSUES IN THE DEVELOPMENT AND RESEARCH OF NEW MEDICINES Pages 648-652.
Graduate supervision
- Supervision of undergraduate research projects of B Pharm students of FAHS, KDU (Since 2021)