Dr. DU Kottahachchi

Diploma in MLT(Ministry of Health), BSc (General) (Peradeniya), MPhill (Colombo), PhD in Experimental Hematology& Mass Spectrometry based Proteomics (Colombo)
Senior Lecturer Gr II
  • Qualifications
  • Qualifications

    • Ph.D ( University of Colombo), 2014
    • M.Phil (university of Colombo), 2007
    • BSc ( University of Peradeniya) (General Degree), 2000
    • Diploma in Medical Laboratory Technology (MLT) (Ministry of Health)
  • Research & Publications
  • Research & Publications

    International Journal publication

    • Darshana Kottahachchi, Lallindra Gooneratne, Anil Jayasekera, Dorota Muth-Pawlak, Robert Moulder, Susumu Y. Imanishib, Ari Ariyaratne, Anne Rokka, Garry L. Corthals. (2015) Quantitative analysis of the erythrocyte membrane proteins in polycythemia vera patients treated with hydroxycarbamide, Eupa Open Proteomics, Volume 7, June 2015, Pages 43-53.
    • D. U. Kottahachchi1, T. R. Ariyaratne, G. A. U. Jayasekera (2014) Mass spectrometry based analysis of erythrocyte membrane associated proteins in chronic myeloid leukemia patients in Sri Lanka, International Letters of Chemistry, Physics and Astronomy, 19(1): 74-86. (www.ilcpa.pl)

    Local Journal publication

    • D. U. Kottahachchi (2010) - Review: Mass Spectrometry - A new technique for Biomarker discovery, Journal     of the Association of Medical Laboratory Technologists (SLAMLT - 2009), in 2010.

    International conferences - Abstracts

    • D. U. Kottahachchi, L. V. Gooneratne, D. D. N. B. Daya, G. A. U. Jayasekera, T. R. Ariyaratne, S. Y. Imanishi, A. Rokka and G. L. Corthals (2012), Comparison of Erythrocyte Membrane Proteins Expression Levels in Polycythemia Vera Patients and Healthy Controls, EuPA/BSPR 2012 Scientific Congress - New Horizons and Applications for Proteomics, July 2012, Glasgow, United Kingdom.
    • D. U. Kottahachchi, L. V. Gooneratne, D. D. N. B. Daya, G. A. U. Jayasekera, T. R. Ariyaratne, S. Y. Imanishi, A. Rokka and G. L. Corthals (2012), Proteomics applications in blood cancer - Polycythemia Vera,   Cancer Proteomics ? part of System Biology (Europe), 16-17, October 2012, Madrid, Spain.
    • D. U. Kottahachchi, L. V. Gooneratne, D. D. N. B. Daya, G. A. U. Jayasekera, T. R. Ariyaratne, S. Y. Imanishi, A. Rokka and G. L. Corthals (2012), Erythrocyte Membranes and proteomics - An Ideal Link to Study Polycythemia Vera, The 22nd Annual BioCity Symposium, August 2012, Turku, Finland.

    Local - Abstracts

    • D. U. Kottahachchi and T. R. Ariyaratne (2010), Feasibility study to identify human plasma proteins using Matrix Assisted Laser Desorption Ionization Time Of Flight (MALDI-TOF) Mass Spectrometry, Annual research symposium (postgraduate), University of Colombo.
    • D. U. Kottahachchi, S. C. A. Abeyakoon, D. D. N. B. Daya, G. A. U. Jayasekera, T. R. Ariyaratne (2006), Investigations of the changes in the erythrocyte membrane associated proteins in Chronic Myeloid Leukemia (CML) using One Dimensional Sodium Dodecyl Sulfate Poly Acrylamide Gel Electrophoresis (1D SDS - PAGE) & Matrix Assisted Laser Desorption Ionization Time Of Flight (MALDI - TOF) mass spectrometry, The Sri Lanka College of Haematologists, 6th Annual Academic Sessions.
    • D. U. Kottahachchi, S. C. A. Abeyakoon,, D. D. N. B. Daya, G. A. U. Jayasekera, T. R. Ariyaratne (2005), Matrix Assisted Laser Desorption Ionization Time Of Flight (MALDI - TOF) mass spectrometric identification of human erythrocyte membrane associated proteins separated by one    dimensional gel electrophoresis, Place - Sri Lanka Association for the Advancement of Science (SLAAS) - 613 / E2.

    PRESENTATIONS/ POSTERS

     International conferences/symposiums (poster presentations)

    • Cancer Proteomics - part of System Biology (Europe), 16-17, October 2012, Madrid, Spain.

     Local conferences/symposiums (Oral presentations)       

    • Annual Research Symposium (postgraduate), Proceedings, University of Colombo, May, 2010.
      • The Sri Lanka College of Haematologists, 6th Annual Academic Sessions, Waters Edge, Capital City, 2006.
      • Sri Lanka Association for the Advancement of Science (SLAAS), Proceedings of the 61st Annual Sessions, The Open University of Sri Lanka, December, 2005.

    AUTHORSHIPS IN BOOKS/ CHAPTERS

          Text Books

    1. D. U. Kottahachchi (2009), Advanced Clinical Hematology (Course Unit MLU 3245) - Department of Health Science, Open University of Sri Lanka.
    2. D. U. Kottahachchi (2009), Immunology (Course Unit MLU 3144) - Department of Health Science, Open University of Sri Lanka.
    3. D. U. Kottahachchi (2009), Principles of Laboratory Management (Course Unit MLU 3242) - Department of Health Science, Open University of Sri Lanka.
    4. D. U. Kottahachchi (2009), Basic Hematology (Course Unit MLU 1148) - Department of Health Science, Open University of Sri Lanka.
    5. D. U. Kottahachchi (2009), Basic Principles of Physics and Laboratory Instrumentation (Course Unit MLU 1143) - Department of Health Science, Open University of Sri Lanka.
    6. D. U. Kottahachchi (2009), Pathology (Course Unit NSU 1116) - Department of Health Science, Open University of Sri Lanka
  • Awards
  • Awards

    • For Ph.D- The fellowship 1 has been funded by International Science programs (ISP), Uppsala University, Sweden, 2011 - December 2011.(Translational Proteomics Research Group, Turku Centre for BiotechnoloUniversity of Turku, Finland)
    • The fellowship 2 has been funded by Exchange by Promoting Quality Education, Research and Training in South and South-   East Asia (EXPERTSASIA), University of Goettingen, Germany, December 2011- April
    •  For M.Phil- The following fellowships have been funded by International Science programs (ISP), Uppsala University,  Sweden, Department of Bio-Chemistry & Molecular Biology, University of Odense, Southern Denmark, Department of  Physics, Angstrom Laboratory, Department of Analytical Chemistry, Bio Medical Center (BMC), Ludwig Institute for Cancer Research (LICR), Bio Medical Center (BMC), Uppsala University, Sweden.

    Research grants and awards

    • Research Assistant, Mass spectrometry Research group, Department of Physics, Faculty of Science, University of Colombo, Colombo 3, Sri Lanka under the research grant from International Science Programs (ISP), Uppsala University, Sweden
  • Working Experience
  • Working Experience

    • More than 11 years of service as a Medical Laboratory Technologist. Enrolled in work related to both Histopathology (One and half years) & Hematology (around 10 years)
    • Engaged in histological work, tissue embedding, tissue section cutting, H&E staining at department of Histopathology (1994-1995) and have good practical knowledge
    • Engaged in special and heavy routine hematological work of inward patients and out patients department, Cancer Hospital, (1995 - 2005). Sound clinical, pathological and practical knowledge in blood & hematological diseases

    Previous academic and administrative posiion

    • Have more than one year experience (2009-2010) as a Consultant, Medical Laboratory Science (MLS) Degree Program, Department of Health Sciences, Faculty of Natural Sciences, Open University, Sri Lanka
    • Have 3 ½ years' experience as a full time member of the teaching staff, School of Medical Laboratory Technology, National Institute of Health Sciences (NIHS), Nagoda, Kalutara, Sri Lanka
    • Have more than 3 years' experience as a part time member of the teaching staff. National Institute of Health Sciences (NIHS), Nagoda, Kalutara, Sri Lanka
    • Conducted lectures and practical sessions in the “Maldivivian Social workers Program” at NIHS in 2007 
  • Contribution
  • Contribution

    Contribution to undergraduate and post graduate education

    • Open university, srilanka
    • University of Ruhuna, Srilanka
    • Have more than 4 years' experience (2008 - 2011 & 2013-2014) as a visiting lecturer & external examiner in Hematology and Transfusion Medicine, Medical Laboratory Science (MLS) Degree Program, Faculty of Allied Health science Degree program, University of Ruruna, Galle, Sri Lanka by conducting lectures and practical in Hematology and Transfusion Medicine

    Contribution to national development

    My long academic and professional carrier (more than 21 years) mainly confined to health development (under national development). The following are the brief descriptions