Dr. Chathuranga Bharathee Ranaweera
Google Scholar
Research Gate
E-mail cbr2704@kdu.ac.lk / cbr2704@gmail.com
Qualifications
Research & Publications
Awards
Working Experience
Memberships
Qualifications
Academic Qualifications
- PhD in Biochemistry & Molecular Biophysics – Kansas State University (USA), Department of Biochemistry and Molecular Biophysics
Thesis- Bacterial AAA+ Disaggregase ClpB: Mechanism and inhibition ( Supervisor, Professor Michal Zolkiewski).
https://krex.k-state.edu/dspace/handle/2097/41435 - MSc in Molecular Medical Microbiology- University of East London
- BSc (Hons) in Biomedical Science- University of East London
- Chartered Institute of Environmental Health (CIEH) UK Level 4 Merit certificate holder in Health and Safety at the workplace.
Professional Qualifications
- Probationary Lecturer at the Faculty of Allied Health Sciences (Medical Laboratory Sciences Department), General Sir John Kotelawala Defence University Sri Lanka.
February 2013- to present date - Laboratory and Workshop Demonstrator for Undergraduate students, in the field of Bioscience at University of East London. October 2011- February 2013.
Research & Publications
- Biochemical characterization of ClpB and DnaK from Anaplasma phagocytophilum https://www.sciencedirect.com/science/article/pii/S1355814524001068
- The Role of Neutrophils, Lymphocytes and Monocytes in Ischemic Heart Disease: Friend or Foe? http://ir.kdu.ac.lk/bitstream/handle/345/7548/Ranaweera%20CB.pdf?sequence=1
- Role played by biochemical and hematological parameters in the prediction of cardiovascular risk http://open.journal4submit.com/id/eprint/3756/1/Nuwanthika1422024AJRB113882.pdf
- Chaperones to the Rescue: Tackling Neurodegenerative Diseases and Potential Therapeutic Applications http://192.248.104.6/bitstream/handle/345/7551/BIO-NEWS_MARCH_2024%20%281%29.pdf?sequence=1&isAllowed=y
- Therapeutic Potential of Carica papaya Linn.: A Comprehensive Review of Its Pharmacological Properties and Health Benefits, with Emphasis on Dengue Fever Healing http://archive.paparesearch.co.in/id/eprint/1936/1/Fernando1212024APRJ112835.pdf
- Evaluation of In vitro Anti-Inflammatory and Antibacterial Properties of Tuberous Roots of Mirabilis jalapa L. Found in Sri Lanka https://journalajrib.com/index.php/AJRIB/article/view/189
- De novo design of a stapled peptide targeting SARS-CoV-2 spike protein receptor-binding domain https://doi.org/10.1039/D3MD00222E
- Repurposing an Anti-Tumor Drug Candidate for Targeting Bacterial ATP-Dependent Proteases DOI: 10.13140/RG.2.2.29382.86080
- Evaluation of Antibacterial Activity of Endemic Jeffreycia zeylanica Plant Found in Sri Lanka https://journalsajrm.com/index.php/SAJRM/article/view/296
- OMICS and Other Advanced Technologies in Mycological Applications https://doi.org/10.3390/jof9060688
- Phytochemical Screening for Medicinal Plants: Guide for Extraction Methods https://journalaprj.com/index.php/APRJ/article/view/216
- De novo design of a stapled peptide targeting SARS-CoV-2 spike protein receptor-binding domain https://pubs.rsc.org/en/content/articlehtml/2023/md/d3md00222e
- Molecular Chaperone ClpB Becomes a Novel Antimicrobial Target https://www.researchgate.net/publication/369013549_Molecular_Chaperone_ClpB_becomes_a_Novel_Antimicrobial_Target_Published_by_Institute_of_Biology_Sri_Lanka_BIO-NEWS_Volume_03_Issue_01_January_2023
- Rich Diversity & Potential Medicinal Value of Endemic Sri Lankan Plant: Jeffreycia zeylanica DOI: 10.9734/aprj/2022/v10i4197
- Mirabilis jalapaLinn.: A Folklore Ayurvedic Medicinal Plant in Sri Lanka https://doi.org/10.9734/aprj/2022/v10i2187
- Review on Artocarpus nobilis Thw. (Moraceae):An Endemic Plant of Sri Lanka https://doi.org/10.9734/aprj/2022/v10i1183
- Antibacterial Activity of Endemic Artocarpus nobilis Thw Found in Sri Lanka https://doi.org/10.9734/sajrm%2F2021%2Fv11i330254
- In vitro Anti-inflammatory Activity of Endemic Artocarpus nobilis Thw Found in Sri Lanka Asian Plant Research Journal 8 (4), 116-122
- Bacterial AAA+ Disaggregase ClpB: Mechanism and inhibition
- Clinicoepidemiological Characteristics of Vitiligo: A Descriptive Cross Sectional Study
- Clitoria ternatea-Shifting Paradigms: From Laboratory to Industry. South Asian Journal of Research in Microbiology, December 2021, DOI:10.9734/SAJRM/2021/v11i230247
- Repurposing p97 inhibitors for chemical modulation of the bacterial ClpB–DnaK bichaperone system. Journal of Biological Chemistry. 2020. Przemyslaw Glaza, Chathurange B. Ranaweera, Sunitha Shiva, Anuradha Roy, Brian V. Geisbrecht, Frank J. Schoenen, Michal Zolkiewski.
- Interaction of substrate-mimicking peptides with the AAA+ ATPase ClpB from Escherichia coli. Archives of Biochemistry and Biophysics.Volume 655, 1 October 2018, Pages 12-17 Chathurange B.Ranaweera,Przemyslaw Glaza,Taihao Yang, Michal Zolkiewski
- In vitro antirheumatoid arthritic activity of aqueous root extract of Clitoria ternatea. Ranaweera, C.B., Pathirana, R., Ambalanduwa,K.C., Jayakody Ralalage, A.C.J. and Ratnasooriya, W.D., 2014. In vitro antirheumatoid arthritic activity of aqueous root extract of Clitoria ternatea. Int. Res. J. Pharm, 5(12), pp.926-928.
- Evaluation of in vitro antibacterial activity of some Sri Lankan medicinal plants .Silva, A.R.N., Dissanayake, D.M.R.K., Ranaweera, C.B., Pathirana, R. and Ratnasooriya, W.D., 2015. Evaluation of in vitro antibacterial activity of some Sri Lankan medicinal plants. Int J, 4, p.54-57. https://ijpras.com/en/issue/2015-volume-4-issue-2
- Antibacterial activity of water extracts of different parts of Morinda citrifolia grown in Sri Lanka. Silva, A.R.N., Ranaweera, C.B., Karunathilaka, R.N., Pathirana, R. and Ratnasooriya, W.D., 2016. Antibacterial activity of water extracts of different parts of Morinda citrifolia grown in Sri Lanka. Int J Sci Res Publ, 6, pp.124-7
- Antibacterial Activity of Aqueous Root, Seed, Flower and Stem Bark Extracts of Acronychia pedunculata Grown in Sri Lanka. Ranaweera, C.B., Karunathilaka, N., Niloshan, A.R., Karunarathna, S., Pathirana, R. and Ratnasooriya, W.D., 2016. Antibacterial Activity of Aqueous Root, Seed, Flower and Stem Bark Extracts of Acronychia pedunculata Grown in Sri Lanka. International journal of pharmaceutical research and allied sciences, 5(2), pp.21-25.
- Use of electronic text books (e-books) by undergraduate students in Sri Lanka: the challenge for academic and research libraries in Sri Lanka.Ranaweera, C.B., Use of electronic text books (e-books) by undergraduate students in Sri Lanka: The Challenge For Academic And Research Libraries In Sri Lanka. International Journal of Recent Advances in Multidisciplinary ResearchVol.03, Issue02, pp.1273-1278,February, 2016
- In vitro effects of aqueous extracts of five Sri Lankan medicinal plants on human erythrocyte membrane stabilisation activity .Chathuranga Bharathee Ranaweera, Anomali Shilpika Vidanagamage, Walimuni Prabhashini Kaushalya abeysekara, Athige Rajith Niloshan silva, Ambalanduwe Kankanamge Chandana, Sirimal Premakumara, Ranjith Pathirana, Wanigaseka Daya Ratnasooriya.. International Journal of Recent Advances in Multidisciplinary Research. 2016 , 2(16), 0486-0489.
- Lack of in vitro antihyaluronidase activity of methanolic leaf extract of Indigofera tinctoria L and methanolic stem bark extract of Stereospermum suaveolens DC. Ranaweera, C.B., Abeysekara, W.P., Pathirana, R. and Ratnasooriya, W.D., 2015. Lack of in vitro antihyaluronidase activity of methanolic leaf extract of Indigofera tinctoria L and methanolic stem bark extract of Stereospermum suaveolens DC. Journal of Pharmaceutical Negative Results, 6(1), p.40.
- In vitro antioxidant activity of methanolic extracts of leaves of Indigofera indica and stem bark of Stereospermum suaveolens grown in Sri Lanka. W.D.Ratnasooriya. Chathuranga Bharathee Ranaweera, W.P.K.M Abeysekara , R.Pathirana. International Journal of Institutional Pharmacy and Life Sciences 5 (2), 128-138.
- In vitro antibacterial activity of hexane, chloroform and methanolic extracts of different parts of Acronychia pedunculata grown in Sri Lanka. R.D. Nimantha Karunathilaka, Athige Rajith Niloshan Silva, Chathuranga Bharathee Ranaweera, D.M.R.K. Dissanayake, N.R.M. Nelumdeniya, Ranjith Pathirana and W. D. Ratnasooriya. International Journal of Advance Research, 2016. 4 (8), 1574-78
- Poster Presentation at 23rd Annual Midwest Stress Response and Molecular Chaperone Meeting on Interaction of substrate-mimicking peptides with the AAA+ATPase ClpB from Escherichia coli 2018. (USA)
- Poster Presentation at University of East London on Antibacterial compounds from Urtica dioica against MRSA infection 2012. (London)
- Poster Presentation at University of Bielefeld on Laboratory training in Scale-up mammalian cell cultivation 2013.( Germany )
- Poster Presentation at University of Bielefeld on Perfusion Cultivation of Chlamydomonas reinhardtii with a Cell Settler in 2 Liter Bioreactor 2013. (Germany)
Awards
Research Awards & Grants
- Postgraduate Research Training University of Applied Sciences Bielefeld Germany.
Working Experience
- Laboratory and Workshop Demonstrator for Undergraduate students, in the field of Bioscience at University of East London. October 2011- February 2013.
Memberships
Memberships In Academic & Professional Bodies
- Chartered Institute of Environmental Health (CIEH) UK