- Qualifications
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Qualifications
- Ph.D ( University of Colombo), 2014
- M.Phil (university of Colombo), 2007
- BSc ( University of Peradeniya) (General Degree), 2000
- Diploma in Medical Laboratory Technology (MLT) (Ministry of Health)
- Research & Publications
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Research & Publications
International Journal publications (Index Journals)
- Darshana Kottahachchi, Lallindra Gooneratne, Anil Jayasekera, Dorota Muth-Pawlak, Robert Moulder, Susumu Y. Imanishi,Ari Ariyaratne, Anne Rokka, Garry L. Corthals.(2015) Quantitative analysis of the erythrocyte membrane proteins in polycythemia vera patients treated with hydroxycarbamide, Eupa Open Proteomics, Volume 7, Pages 43–53. https://www.sciencedirect.com/science/article/pii/S2212968515000100
- Bhawani Alvitigala, Darshana Kottahachchi, Namal Wijesinghe (2018) A study of association between plateletvolume indices and ST elevation myocardial infarction, International Journal of Cardiology: Heart & Vasculature. https://www.sciencedirect.com/science/article/pii/S2352906718301039?via%3Dihub
- Nimesha N. Senadeera, Chathuranga B. Ranaweera, Inoka C. Perera and Darshana U. Kottahachchi (2024) Review: Biochemical Insights and Clinical Applications of Ische-mia- Modified Albumin in Ischemic Conditions, Journal of Vascular Diseases, 3(3), 245-266; https://doi.org/10.3390/jvd3030020
- Mohammad Azam Mansoor, Tonje Holte Stea, Audun Slettan,Erandie Perera, Ridmi Maddumage, Darshana Kottahachchi, Dhikra SaleemAli, Rona Cabo, and Rune Blomhoff (2024) Impact of single nucleotide polymorphisms (SNPs) in antioxidant-enzyme genes on the concentrations of folate, homocysteine and glutathione in plasma from healthy subjects after folic acid supplementation – a randomized controlled crossover trial, Genes & Nutrition volume 20, Article number: 1 (2025). https://genesandnutrition.biomedcentral.com/articles/10.1186/s12263-024-00761-6
- W. K. T. Nuwanthika, D. I. K. Welivitigoda, S. P. N. N. Senadeera, D. U. Kottahachchi, C. B. Ranaweera and N. Wijesinghe (2024) Role Played by Biochemical and Hematological Parameters in the Prediction of Cardiovascular Risk, Asian Journalof Research in Biochemistry, Volume 14, Issue 2, Page 7-17, 2024; Article no.AJRB.113882. https://journalajrb.com/index.php/AJRB/article/view/278
- S. P. N. N. Senadeera, D. S. H. S. Peiris, D. T. K. Fernando, D. U. Kottahachchi, and C. B. Ranaweera (2024) The Role of Neutrophils, Lymphocytes and Monocytes in Ischemic Heart Disease: Friend or Foe?, Cardiology and Angiology: An International Journal,Volume 13, Issue 2, Page 62-72, 2024; Article no.CA.116332
ISSN: 2347-520X, NLM ID: 101658392 DOI: 10.9734/CA/2024/v13i2407 - K. K. P Zoysa,B. H. H.,Geethal, Ratnamalala V and Kottahachchi DU (2024) Prediction of Timely Decaying Efficiency of Factor VIII Replacement Therapy Using Activated Partial Thromboplastin Time (aPTT) Test in Hemophilia a Patients Undergoing Treatment at the National Hospital of Sri Lanka (NHSL), Asian Hematology Research Journal, Volume 7, Issue 4, Page 250-260, 2024; Article no.AHRJ.128531.
https://www.journalahrj.com/index.php/AHRJ/article/view/188/383 - Akarsha Peiris,Sapna Wickramasinghe, YasinthaCosta, Darshana Kottahachchi (2023) Proposing an accuratequantification method for myeloperoxidase stainingon peripheral blood smears with varying hemoglobin and absolute neutrophil counts, International Journal of Research Publications, 120(01); 53-54. https://ijrp.org/paper-detail/4481
- Darshana Kottahachchi, Chamila Nandasena, Sachini Gallage, Inoka C Perera, Sasikala Suresh. (2021) A review on the Role of FLT3/FL System in Non-Hodgkins Lymphoma, International Journalof Research Publications, Volume 70: (1). https://ijrp.org/paper-detail/1740, DOI: 10.47119/IJRP100701220211739
- Darshana Kottahachchi, Erandie Perera, Ridmi Maddumage, Mohammad Azam Mansoor. (2021) Review: Oxidative Stress in Type 2 Diabetes Mellitus – A Key Factor for Major Complications, International Journal of Research Publications, Volume 70: (1), https://ijrp.org/paper-detail/1741 DOI: 10.47119/IJRP100701220211740
- Darshana Kottahachchi, Ridmi Maddumage Erandie Perera, Mohammad Azam Mansoor (2021) Review: Chronic Kidney Disease and Diabetic Nephropathy - Major Complications of Type 2 Diabetes Mellitus, International Journal of Scientific Research and Engineering Development, Volume 4: (03), 2581-7175. http://www.ijsred.com/volume4/issue3/IJSRED-V4I3P19.pdf
- Manoj A. Wijesekara, Lallindra V. Gooneratne, Sharmila Jayasena , Darshana U. Kottahachchi, Dananjaya Perera , Anoma Jayasiri , Manujasri C. Wimalachandra , Ayuma U. Hewageegana , Preethi Soysa (2023) Molecular Basis and Potential Molecular Mechanisms of Action in NaturalProducts as Therapeutic Agents Towards MultipleMyeloma, Tropical Journal of Natural Product Research, 7(2): 2104-2115. https://www.tjnpr.org
- Darshana Kottahachchi, Chamila Nandasena, Sachini Gallage, Inoka C Perera, Darshan De Silva, Sasikala Suresh. (2021) A Review on the Role of C Kit /SCF System in Hematological Malignancies, International Journalof Innovative Scienceand Research Technology, Volume 06: (2), 979-983 (IJISRT21FEB565.pdf, DOI: ISSN No:-2456-2165. https://ijisrt.com/assets/upload/files/IJISRT21FEB565.pdf
- Darshana Kottahachchi, Sadhani Sandarenu, Chamila Nandasena, Upekshi Kankanamge, Trilicia Withanawasam. (2021),Review: Combat againstCOVID-19 Complications -Traditional Plant Lantana camara, International Journalof Innovative Scienceand Research Technology, Volume 6: (1), 1244-1248. https://ijisrt.com/assets/upload/files/IJISRT21JAN698.pdf
- Darshana Kottahachchi, Tharushika Deshani Hewapathirana, Thisali Chandula Perera, Shashikala Suresh (2024) Review: Mononuclear Cells as a Predictive Marker for Stem Cells in Autologous Peripheral Blood Stem Cell Transplantation in Multiple Myeloma, Medical Laboratory Journal.
- JKC Shyalika, PPNV Kumara,DU Kottahachchi (2019) Statisticalmorphological analysis based supervised classification algorithm for diagnosing acute lymphoblastic leukemia,Journal of Theoretical and Applied Information Technology, 98(18): 3741-3755. https://www.researchgate.net/publication/344466528
International Conference Proceedings (Full paper)
- Chathurangi Shayalika, Nandana Pathirage and Darshana Kottahachchi (2017) An Image Processing Application for Diagnosing Acute Lymphoblastic Leukemia(ALL), Published on the 10th International ResearchConference on “Changingdynamics in the global environment: Challenges & Opportunities” to be held on 3rd & 4th August 2017 at General Sir John Kotelawala Defence University (KDU), Ratmalana, Sri Lanka. (https://www.researchgate.net/publication/332549962_An_Image_Processing_Application_for_ Diagnosing_Acute_Lymphoblastic_Leukemia_ALL/link/5cbc6c4092851c8d22fad8a0/download)
Local Journal publication
- Wijesekara M. A., Soysa P., Jayasena S., Kottahachchi D.U. , Perera D., Jayasiri A.P.A , Gooneratne, L.V. (2022)In vitro screening of antioxidant and anti-inflammatory capacities of plant extract Curculigo orchioides Gaertn, Sri Lanka Journal of Indigenous Medicine (SLJIM), 07(01); 554-565. http://sljim.fim.cmb.ac.lk/journal/index.php/sljim/article/view/58
- Wijesekara M.A., Soysa P., Jayasena, S., Kottahachchi D.U., Perera D., Jayasiri A.P.A., Wimalachandra M.and Gooneratne L.V. (2022) Protective activity of Tinospora cordifolia (Willd.) Hook. f. and Thoms.and Withania somnifera(L.) Dunal againstlipid peroxidation, protein oxidation and deoxyribose oxidation, Sri Lanka Journal of Indigenous Medicine; 07 (02): 636 – 644. http://sljim.iim.cmb.ac.lk/journal/index.php/sljim/article/view/78/44
- D. U. Kottahachchi (2010) Review: Mass Spectrometry – A new technique for Biomarker discovery, Journal of the Association of Medical Laboratory Technologists (SLAMLT - 2009), in 2010.
Internationalconferences – Abstracts
- Sara Iqbar, Anisha Fernando, Darshana Kottahachchi, Trileeshiya Withanawasam (2023) A Study on the Hemolysis Effect on Red Cell Concentrates derived from Whole Blood within the storageperiod at Department of Transfusion Medicine,University Hospital, GeneralSir John Kotelawala Defence University. Sri Lanka, Annual Congress of Asian Association of Transfusion Medicine (AATM – 2023).
- Chathurangi Shayalika, Nandana Pathirage and Darshana Kottahachchi (2017), An Image Processing Application for Diagnosing Acute Lymphoblastic Leukemia (ALL), The Sixth International Conference on Advancement of Development Administration 2017- Social Sciences and Interdisciplinary Studies (The 6th ICADA 2017—SSIS), June 2017, National Institute of Development Administration (NIDA), Bangkok, Thailand.
- D. U. Kottahachchi, L. V. Gooneratne, D. D. N. B. Daya, G. A. U. Jayasekera, T. R. Ariyaratne, S. Y. Imanishi, A. Rokka and G. L. Corthals (2012), Comparison of Erythrocyte Membrane Proteins Expression Levels in Polycythemia Vera Patients and Healthy Controls,EuPA/BSPR 2012 Scientific Congress – New Horizons and Applications for Proteomics, July 2012, Glasgow, United Kingdom. (http://www.bspr.org/sites/default/files/bspr2012/EUPA2012Abstracts_final.pdf (P039))
- D. U. Kottahachchi, L. V. Gooneratne, D. D. N. B. Daya,G. A. U. Jayasekera, T. R. Ariyaratne, S. Y. Imanishi, A. Rokka and G. L. Corthals (2012),Proteomics applications in blood cancer - Polycythemia Vera, Cancer Proteomics – part of System Biology (Europe), 16-17, October 2012, Madrid, Spain.
- D. U. Kottahachchi, L. V. Gooneratne, D. D. N. B. Daya, G. A. U. Jayasekera, T. R. Ariyaratne, S. Y. Imanishi, A. Rokka and G. L. Corthals (2012),Erythrocyte Membranes and proteomics – An Ideal Link to Study Polycythemia Vera, The 22nd Annual BioCity Symposium, August 2012, Turku, Finland.
Local Conference Proceedings (Full paper)
- H.N. Ranasinghe, V.W.Liyanarachchi, U.S.Rahubadda, D.U. Kottahachchi (2024) A Review of Development of a Novel RBC Histogram and a RDW-CV Parameter for Improved Diagnosis and Monitoring of Iron Deficiency Anemia using a Computational Mathematical Tools, 17th International Research Conference 2024 in General Sir John Kotelawala Defence University (KDU), Ratmalana, Sri Lanka (IRC 2024).
- R.M.D.K Rathnayaka, R.M.D Seneviratne, D. Kottahachchi and Y. Costa (2020) Correlation between Hemoglobin Concentration and Absolute Reticulocyte count of adolescent female iron deficient patients at Colombo North Teaching Hospital, 13th International Research Conference on “Holistic Approach to National Growth and Security”, General Sir John Kotelawala Defence University (KDU), Ratmalana, Sri Lanka.
- T.D. Hewapathirana, T.C. Perera, S. Suresh, D.U. Kottahachchi (2024) Study The Possibility Of using Post-Mobilization Day 8 and Hematopoietic Progenitor Cell Parameter as Alternative Determinants for Autologous Peripheral Blood Stem Cell Transplantation in Multiple Myeloma, Published on the 12th YSF symposium on “Integration of Science, Technology and Innovation for a Better Sustainable Economy” held in January 2024.
Local journal paperabstracts
- D. U. Kottahachchi, S. C. A. Abeyakoon, D. D. N. B. Daya, G. A. U. Jayasekera, T. R. Ariyaratne (2006), Investigations of the changes in the erythrocyte membrane associated proteinsin Chronic Myeloid Leukemia (CML) using One Dimensional Sodium Dodecyl Sulfate Poly Acrylamide Gel Electrophoresis (1D SDS – PAGE) & Matrix Assisted Laser Desorption Ionization Time Of Flight (MALDI – TOF) mass spectrometry, The Sri Lanka College of Haematologists, 6th Annual Academic Sessions. (https://www.res.cmb.ac.lk/physics/barlo-daya/pubs/investigation-of-the-changes-and- identification-of-erythrocyte-membrane-associated-proteins-in-healthy-individuals-and-chronic-myeloid-leukemia-cml-patients-using-one-dimensional-sodium-dodecyl-sulp/)
- D. U. Kottahachchi, S. C. A. Abeyakoon,, D. D. N. B. Daya, G. A. U. Jayasekera, T. R. Ariyaratne (2005), Matrix Assisted Laser Desorption Ionization Time Of Flight (MALDI – TOF) mass spectrometric identification of human erythrocyte membrane associated proteins separated by one dimensional gel electrophoresis, Sri Lanka Association for the Advancement of Science (SLAAS) – 613 / E2.
Conference Proceedings (Local)– Abstracts
- Zoysa KKP, Geethal BHH, Kottahachchi DU (2024) Prediction of the decaying Factor VIII levels in post factor VIII replacement therapyusing Activated PartialThromboplastin Time Test in Hemophilia A patients undergoing treatment at The National Hospitalof Sri Lanka, Proceeding of the International Open University Research Sessions (iOURS 2024).
- Zoysa KKP, Geethal BHH, Kottahachchi DU (2024) Prediction of the maximum time that could maintain the efficiency of Factor VIII replacement therapy using Activated Partial Thromboplastin Time Test in Hemophilia A patients undergoing treatment at the National Hospital of Sri Lanka, International Research Conference on Healthy delights, University of Jaffna.
- R.D.K.K. Kumarasinghe, H.N. Ranasinghe, K.G.K.G. Jayawardana, I. Somaratne, D.U. Kottahachchi (2024)An attempt to establish correlations among platelets and platelet indices in covid-19 patients undergoing treatments beyond seven days at University Hospital- General Sir John Kotelawala Defence University (UH-KDU), 12th YSF SYMPOSIUM2024, in Young Scientists Forum, National Science and Technology Commission.
- Nandasena C, Jayathilake PWDCC, Dharmarathne G, Suresh S De Silva, AD,Perera IC, Kottahachchi DU (2023) Comparison of the presenceof FLT3 receptor on peripheral blood mononuclear cells between newly diagnosed non-Hodgkin lymphoma patients and healthy individuals, Proceedings of the 12th Annual Scientific Sessions of the IBMBB, University of Colombo, Sri Lanka.
- T.D. Hewapathirana, T.C. Perera, R. Tudugala, S. Suresh, D.U. Kottahachchi (2023) An Attempt to Establish a Cutoff Value for Peripheral Blood Hematopoietic Progenitor Cell Count to Predict the Viable CD34 Count in Multiple Myeloma Patients Undergoing Autologous Peripheral Blood Stem Cell Transplantation, Proceedings of the International Conference on Applied and Pure Sciences – 2023. University of Kelaniya, Sri Lanka – Paper ID 58 (icaps 2023). http://repository.kln.ac.lk/handle/123456789/26974
- Peiris M.U.A, Wickramasinghe P.W.W.M.S.D, Tudugala R, Costa Y, Kottahachchi D.U (2023) Establishment of Associations in between Myeloperoxidase levels in Neutrophils and Mean Cell Hemoglobin Concentration in Varying Hemoglobin Concentrations of Patients Attending Haematology Clinic, Colombo North Teaching Hospital, Ragama, Sri Lanka, Proceedings of the International Conference on Appliedand Pure Sciences– 2023. University of Kelaniya, Sri Lanka – Paper ID 124 (icaps 2023).
- Nandasena CK, Jayathilake PWDCC, Suresh S, De Silva AD, Perera IC, Kottahachchi DU (2023) Preliminary Study on the Association between FLT3 Ligand Level in Plasma and Peripheral White Blood Cell Counts in Non-Hodgkin Lymphoma Patients and Healthy Individuals, 16th International Research Conference -General Sir John Kotelawala Defence University.
- C.K. Nandasena, P.W.D.C.C. Jayathilake, S. Suresh, A.D. De Silva, I.C. Perera, D.U. Kottahachchi (2023) Preliminary study to detect the associations between FLT3 positivity/negativity on peripheral blood mononuclear cells, FLT3 ligand level in plasma, and peripheral white blood cell counts in newly diagnosed NHL patients and healthy individuals, Annual Research Symposium 2023, Faculty of Science, University of Colombo, Sri Lanka.
- Peiris M.U.A, Wickramasinghe P.W.W.M.S.D, Tudugala R, Costa Y, Kottahachchi D.U (2023) Establishing a Cut-off Value for Myeloperoxidase Levels of Peripheral Blood Neutrophils with Varying Hemoglobin and Mean Cell Hemoglobin Concentration, International Research Symposium Faculty of Allied Health Sciences, University of Ruhuna, Sri Lanka (iRuFARS-2023).
- Warnakulasuriya N.V, Wanigasinghe D.N, Tudugala R, Herath P, Kottahachchi D.U. (2023) Correlations in betweenPerıpheral Blood and Bone MarrowParameters of B-ALL Patıents durıng Post Inductıon Chemotherapy, International Research Symposium Faculty of Allied Health Sciences, University of Ruhuna, Sri Lanka (iRuFARS-2023).
- Welivitigoda D.I.K, Wakwella T.N, Senadeera S.P.N.N, Ranaweera C.B, Kottahachchi D.U, Wijesinghe N. (2023) An Attempt to Find Out an Association in-between HDL/LDL Ratio and 10-year Predicted Cardiovascular Risk Using ASCVD Risk Estimator, International Research Symposium Faculty of Allied Health Sciences, University of Ruhuna, Sri Lanka (iRuFARS-2023).
- Hewapathirana T.D, Perera T.C, Suresh. S, Kottahachchi D.U. (2023) Predıction of Vıable CD34 Count in HarvestedProduct/Perıpheral Blood by Perıpheral Blood Progenıtor Count ofAutomated Haematology Analyzerin Multiple MyelomaPatients Undergoing Autologous Peripheral Blood Stem Cell Transplantation, International Research Symposium Faculty of Allied Health Sciences, University of Ruhuna, Sri Lanka (iRuFARS-2023).
- H.N. Ranasinghe, R.D.K.K. Kumarasinghe, K.G.K.G. Jayawardana, I. Somaratne, D.U. Kottahachchi (2023) Detection of the Effects on Platelet Associated Indices in the Absence of Thrombocytopenia in COVID-19 Patients undergoing treatments at University Hospital General Sir John Kotelawala DefenceUniversity (UH-KDU), Proceeding of the International Open University Research Sessions (iOURS 2023).
- Thilini Wakwella, Dinithi Welivitigoda, Ranga Tudugala, Nimesha Senadeera, Chathuranga Ranaweera, Darshana Kottahachchi, Namal Wijesinghe (2023)An Attempt to Assess The 10- Year Risk for Atherosclerotic Cardiovascular Disease from Total Cholesterol to High- Density Lipoprotein Ratio Among a Group of Health and Administrative Staff of University Hospital-KDU, Proceeding of the International Open University Research Sessions (iOURS 2023).
- N.V. Warnakulasuriya, D.N. Wanigasinghe, R. Tudugala, P. Herath, D.U. Kottahachchi (2023), Study the Variations of Lymphocytes in Peripheral Bloodand Bone Marrowin Acute Lymphoblastic Leukemia Patients Undergoing the Induction Phase of the Chemotherapy, Proceeding of the International Open University Research Sessions (iOURS 2023).
- T.D. Hewapathirana, T.C. Perera, S. Suresh, D.U. Kottahachchi (2023) An Attempt to Establish a Cutoff Value for Peripheral Blood Absolute Mononuclear Cell Count to Predict the Viable CD34 Count in Multiple Myeloma Patients Undergoing Autologous Peripheral Blood Stem Cell Transplantation, Proceeding of the International Open University Research Sessions (iOURS 2023).
- Wickramasinghe P.W.W.M.S.D, Peiris M.U.A, Tudugala R, Costa Y, Kottahachchi D.U (2023) Existence of Myeloperoxidase in Peripheral Blood Neutrophils of Anemic Patients Attending Haematology Clinic,Colombo North TeachingHospital, Ragama, Sri Lanka, 9th International Conference of Sabaragamuwa University of Sri Lanka (ICSUSL 2023).
- Ranasinghe H.N, Kumarasinghe R.D. K. K, Jayawardana K. G.K.G, Somarathne I, Kottahachchi D.U. (2023) Correlation of Platelet and Platelet Indices between Male and Female Covid-19Patients Undergoing Treatments at University HospitalGeneral Sir John Kotelawala Defence University, 9th International Conference of Sabaragamuwa University of Sri Lanka (ICSUSL 2023).
- Wakwella T.N, Welivitigoda D.I.K, Tudugala R, Senadeera S.P.N.N, Ranaweera C.B, Kottahachchi D.U, Wijesinghe N. (2023) An Attempt to Assess the 10-Year Risk for Atherosclerotic Cardiovascular Disease from Total Cholesterol To High-Density Lipoprotein Ratio Among a Group of Health and Administrative Staff of University Hospital-KDU, 9th International Conference of Sabaragamuwa University of Sri Lanka (ICSUSL 2023).
- Welaratne G.I, Gamage P.C.U, Dulshika G.D.S, Silva D.D, Kottahachchi D. (2023) Establishment of associations among BCR-ABL Levels, Neutrophil Alkaline Phosphatase Score and Absolute Neutrophil Count of Chronic Myeloid Leukemia Patients Undergoing Treatment at Apeksha Hospital Maharagama, Sri Lanka, 9th International Conference of Sabaragamuwa University of Sri Lanka (ICSUSL 2023).
- Hewapathirana T.D, PereraT.C, Suresh S, Kottahachchi D.U. (2023)Establishment of Cutoff Value for Peripheral Blood Absolute Mononuclear Cell Count by Viable Cd34 Cells/Kg in Harvested Product of Patients with Multiple Myeloma Undergoing Autologous Peripheral Blood Stem Cell Transplantation, 9th International Conference of Sabaragamuwa University of Sri Lanka (ICSUSL 2023).
- Warnakulasuriya, NV, Wanigasinghe DN, Tudugala R, Herath P, Kottahachchi DU (2023) An Attempt to establish Correlations in between Peripheral Blood and Bone Marrow Parameters of T-ALL Patients during Post Induction Chemotherapy, 9th International Conference of Sabaragamuwa University of Sri Lanka (ICSUSL 2023).
- Kumarasinghe RDKK, Ranasinghe HN, Jayawardana KGKG, Kottahachchi DU, Somarathne I (2023)Detection of the effects on platelets indiceson COVID-19 patientsat the University Hospital General Sir John Kotelawala Defence University (UH-KDU), International Research Conferences in HealthSciences-2023 in University of Sri Jayewardenepura (IRHCS 2023).
- Wijesekara M. A., Soysa P., Jayasena S., Kottahachchi D.U. , Perera D., Jayasiri A.P.A, Gooneratne, L.V. (2022) In vitro screening of antioxidant and anti-inflammatory activities of plant extracts Adenanthera pavonina, 27th International Forestry and Environment Symposium 2023, University of Colombo Sri jayawardenapura, Sri Lanka.
- S. P. N. N. Senadeera, U. D. Rodrigo, L. M. Samarathunga, J. L. K. Jayasinghe, K. D. R. N. Kalubowila, N. I. Abeyasinghe, D. U. Kottahachchi, J. V. P. Fernando, J. K. D. S. Jayanetti. (2022) Raman spectroscopy analysis of Bovine Serum Albumin using electrodeposited copper on Indium Tin Oxide as a SERS substrate, Annual Research Symposium 2022, Faculty of Technology, University of Colombo, Sri Lanka.
- A.A.S.R. Adikari, N.H.LA. Nawarathna, K.M.I. Fernando, B.M.P.P.M. Abeypala, D.U. Kottahachchi, S. Gunathilaka (2021)An attempt to study the behavior of plasma Hemoglobin in post transfusion iron chelated state in beta thalassemia major patients at Thalassemia Unit Kurunegala, Proceedings of the 30th Anniversary Academic Session Conference. Faculty of Medicine, University of Kelaniya, Sri Lanka, Vol 77, Page 19. (http://repository.kln.ac.lk/handle/123456789/24119)
- MV Munasinghe, NAR De Silva, SJMSH Thaldena, KM Hettiarachchi, R Pullaperuma, DU Kottahachchi (2021) Haematological indices and their correlation with fasting blood sugar level in type 2 DiabetesMellitus patients in Teaching HospitalKarapitiya, Galle, Sri Lanka, Proceedings of the 30th Anniversary Academic Session Conference. Faculty of Medicine, University of Kelaniya, Sri Lanka, Vol 77, Page 73 (http://repository.kln.ac.lk/handle/123456789/24022)
- AASR Adikari, NHIA Nawarathna, KMI Fernando, BMPPM Abeypala, DU Kottahachchi, S Gunathilaka (2021) An attempt to Detection of Iron Overloadand Its Complications in Beta Thalassemia MajorPatients at Thalassemia Unit Kurunegala by Investigating Some of the Laboratory Parameters, "Security, Stability and National Development in the New Normal" at 14th International Research Conference (IRC) General Sir John Kotelawala Defence University (KDU) in September 2021. Ratmalana, Sri Lanka. (http://ir.kdu.ac.lk/handle/345/4675)
- L. Welikanna, M. Wijesekara, P. Soysa, L. Gooneratne, D. Perera, S. M. T. Jayasena, A. M. Wickramasuriya and D. Kottahachchi (2021) In vitro screening of total phenoliccontent and antioxidant capacity of soups prepared by commercially available traditional rice varieties in Sri Lanka, 5th International Research Conference “Exploring Potentials in Challenging Periods”, Uva Wellassa University, Sri Lanka.
- A. Jayasiri, D. Perera, D. U. Kottahachchi, S. Jayasena, P. Soysa, M. A. Wijesekara, L. V. Gooneratne (2020) In vitro screening of total phenolic content, flavonoid content, free radical scavenging capacity, and inhibition of lipid peroxidation of Cleistanths collinus, Annual Research Symposium 2020, Faculty of Medicine, University of Colombo, Sri Lanka.
- A. Jayasiri, D. Perera, D. U. Kottahachchi, S. Jayasena, P. Soysa, M. A. Wijesekara, L. V. Gooneratne (2020) In vitro screening of antioxidant capacity, inhibition of lipid peroxidation, inhibition of protein oxidation, and cytotoxicity of different extracts of Bauhinia purpurea on human bone marrow cells, Annual Research Symposium 2020, Faculty of Medicine, University of Colombo,Sri Lanka. (https://med.cmb.ac.lk/res-sym2020/)
- Wijesekara M. A., Soysa P., Jayasena S., Kottahachchi D.U. , Perera D., Jayasiri A, Gooneratne, L.V. (2020)OP-20 – in vitro screeningof total phenolicacid content, flavonoid content, free radical scavenging capacity, and inhibition of lipid peroxidation of Cleistanths collinus, Annual ResearchSymposium 2020, Facultyof Medicine, University of Colombo, Sri Lanka.
- R.M.D.K Rathnayaka, R.M.D Seneviratne, D. Kottahachchi and Y. Costa (2020) Correlation between Hemoglobin Concentration and Absolute Reticulocyte count of adolescent female iron deficient patients at Colombo North Teaching Hospital, 13th International Research Conference on “Holistic Approach to National Growth and Security”, General Sir John Kotelawala Defence University (KDU), Ratmalana, Sri Lanka.
- Wijesekara M. A., Soysa P., Jayasena S., Kottahachchi D.U. , Perera D., Jayasiri A.P.A , Gooneratne, L.V. (2020) In vitro screening of antioxidant capacity of different extracts of Bauhinia purpurea on human bone marrow cells, Faculty Research Symposium-2020, University of Colombo, Sri Lanka.
- L. Welikanna, S. Gunasekera, E.M.M.M.B. Ekanayake, A. Katuwawala, G. A. U. Jayasekera, T. L. S. Tirimanne, S. M. T. Jayasena, P. Soysa, D. Perera, D. Kottahachchi, L. Gooneratne, A. M. Wickramasuriya (2020) PP18 - In silico characterization of putativeuncharacterized protein FLJ37218 and its association with multiple myeloma,Annual Research Symposium 2020, Faculty of Medicine, University of Colombo, Sri Lanka. (https://med.cmb.ac.lk/res- sym2020/)
- Anisha Fernando, Rasarathnam Ganesananthan, T Sooriyakumar, Darshana Kottahachchi (2019) Study the effect of In-vitro haemolysis in Prothrombin Time test resultsusing photo- optical method in warfarin patients and healthy controls at Department of Haematology Teaching Hospital Jaffna, 12th International Research Conference (IRC), General Sir John Kotelawala Defence University (KDU), Ratmalana, Sri Lanka.
- Lakmal PKS, Chathuranga KGM, Kottahachchi DU, Suresh S. (2018) A feasibility study to develop a rapid method to measure erythrocyte sedimentation rate among patients in Apeksha Hospital, Maharagama, Sri Lanka, International Conference of Health Sciences 2018, Faculty of Health Sciences, Sri Jayawardenapura. (PP 51)
- A. I. Katuwawala, L. V. Gooneratne, S. S. B. D. P Soysa, D. Kottahachchi, G. A. U. Jayasekera (2017) Analysis of protein profiles of plasma cells in patients with multiple myeloma, Technology for Environmental Sustainability - The First Annual Research Symposium of the Faculty of Technology, Sri Lanka.
- D. U. Kottahachchi and R. S. Jayatilake (2016), Case Report: The First Peripheral Blood Stem Cell Transplantation for Multiple Myeloma in Sri Lanka, 9th International Research Conference on “Professional Integration for a secure Nation”held on 8th & 9th September 2016 at General Sir John Kotelawala Defence University (KDU), Ratmalana, Sri Lanka.
- D. U. Kottahachchi and T. R. Ariyaratne (2010), Feasibility study to identify human plasma proteins using MatrixAssisted Laser Desorption Ionization Time Of Flight (MALDI-TOF) Mass Spectrometry, Annual research symposium (postgraduate), University of Colombo, Sri Lanka. (http://archive.cmb.ac.lk:8080/research/handle/70130/371)
Text Books/e-Books (Chapters):
As an Editor
- D.U. Kottahachchi (2018), Advanced Haematology (CourseUnit MDU5401) in– Department of Medical Laboratory Science, faculty of Health Science, Open University of Sri Lanka.
As a Co author
- D.U. Kottahachchi et al. (2015),Advanced Clinical Haematology Volume I (CourseUnit MLU3245) – Department of Health Science, Open University of Sri Lanka.
- D.U. Kottahachchi et al. (2015), Advanced Clinical Haematology Volume II (Course Unit MLU3245) – Department of Health Science, Open University of Sri Lanka.
- D.U. Kottahachchi et al. (2014),Basic Haematology (CourseUnit MLU1148) – Department of Health Science, Open University of Sri Lanka.
- D.U. Kottahachchi et al. (2014), Immunology (Course Unit MLU3144) – Department of Health Science, Open University of Sri Lanka.
- D.U. Kottahachchi et al. (2014),Principles of Laboratory Management (Course Unit MLU1246) – Department of Health Science, Open University of Sri Lanka.
- D. U. Kottahachchi etal. (2009), Pathology(Course Unit NSU1116)– Department of Health Science, Open University of Sri Lanka.
- Awards
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Awards
- For Ph.D- The fellowship 1 has been funded by International Science programs (ISP), Uppsala University, Sweden, 2011 - December 2011.(Translational Proteomics Research Group, Turku Centre for BiotechnoloUniversity of Turku, Finland)
- The fellowship 2 has been funded by Exchange by Promoting Quality Education, Research and Training in South and South- East Asia (EXPERTSASIA), University of Goettingen, Germany, December 2011- April
- For M.Phil- The following fellowships have been funded by International Science programs (ISP), Uppsala University, Sweden, Department of Bio-Chemistry & Molecular Biology, University of Odense, Southern Denmark, Department of Physics, Angstrom Laboratory, Department of Analytical Chemistry, Bio Medical Center (BMC), Ludwig Institute for Cancer Research (LICR), Bio Medical Center (BMC), Uppsala University, Sweden.
Research grants and awards
- Research Assistant, Mass spectrometry Research group, Department of Physics, Faculty of Science, University of Colombo, Colombo 3, Sri Lanka under the research grant from International Science Programs (ISP), Uppsala University, Sweden
- Working Experience
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Working Experience
- More than 11 years of service as a Medical Laboratory Technologist. Enrolled in work related to both Histopathology (One and half years) & Hematology (around 10 years)
- Engaged in histological work, tissue embedding, tissue section cutting, H&E staining at department of Histopathology (1994-1995) and have good practical knowledge
- Engaged in special and heavy routine hematological work of inward patients and out patients department, Cancer Hospital, (1995 - 2005). Sound clinical, pathological and practical knowledge in blood & hematological diseases
Previous academic and administrative posiion
- Have more than one year experience (2009-2010) as a Consultant, Medical Laboratory Science (MLS) Degree Program, Department of Health Sciences, Faculty of Natural Sciences, Open University, Sri Lanka
- Have 3 ½ years' experience as a full time member of the teaching staff, School of Medical Laboratory Technology, National Institute of Health Sciences (NIHS), Nagoda, Kalutara, Sri Lanka
- Have more than 3 years' experience as a part time member of the teaching staff. National Institute of Health Sciences (NIHS), Nagoda, Kalutara, Sri Lanka
- Conducted lectures and practical sessions in the “Maldivivian Social workers Program” at NIHS in 2007
- Contribution
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Contribution
Contribution to undergraduate and post graduate education
- Open university, srilanka
- University of Ruhuna, Srilanka
- Have more than 4 years' experience (2008 - 2011 & 2013-2014) as a visiting lecturer & external examiner in Hematology and Transfusion Medicine, Medical Laboratory Science (MLS) Degree Program, Faculty of Allied Health science Degree program, University of Ruruna, Galle, Sri Lanka by conducting lectures and practical in Hematology and Transfusion Medicine
Contribution to national development
My long academic and professional carrier (more than 21 years) mainly confined to health development (under national development). The following are the brief descriptions